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HelpTest Code NFLC Neurofilament Light Chain, Plasma
Specimen Required
Collection Container/Tube: Lavender top (EDTA)
Submission Container/Tube: Plastic screw-top vial
Specimen Volume: 1.5 mL
Collection Information: Centrifuge and aliquot plasma into a plastic vial. Do not submit specimen in original tube.
Specimen Stability Information: Frozen (preferred) 16 months/Refrigerated 7 days
Secondary ID
616854Useful For
Assessing neuronal damage related to various neurodegenerative diseases
Method Name
Digital Immunoassay
Reporting Name
Neurofilament Light Chain, PSpecimen Type
Plasma EDTASpecimen Minimum Volume
0.75 mL
Specimen Stability Information
| Specimen Type | Temperature | Time | Special Container |
|---|---|---|---|
| Plasma EDTA | Frozen (preferred) | ||
| Refrigerated | 7 days | ||
Reject Due To
| Gross hemolysis | Reject |
| Gross lipemia | OK |
| Gross icterus | OK |
Reference Values
<2.5 years: ≤12.8 pg/mL
2.5 to 4 years: ≤11.8 pg/mL
5 to 9 years: ≤10.4 pg/mL
10 to 14 years: ≤8.8 pg/mL
15 to 19 years: ≤9.2 pg/mL
20 to 24 years: ≤10.4 pg/mL
25 to 29 years: ≤11.9 pg/mL
30 to 34 years: ≤13.5 pg/mL
35 to 39 years: ≤15.3 pg/mL
40 to 44 years: ≤17.3 pg/mL
45 to 49 years: ≤19.7 pg/mL
50 to 54 years: ≤22.4 pg/mL
55 to 59 years: ≤25.4 pg/mL
60 to 64 years: ≤28.8 pg/mL
65 to 69 years: ≤32.7 pg/mL
70 to 74 years: ≤37.1 pg/mL
75 to 79 years: ≤42.1 pg/mL
80 to 84 years: ≤ 47.8 pg/mL
≥85 years: ≤54.3 pg/mL
Day(s) Performed
Monday, Wednesday, Friday
Report Available
1 to 7 daysPerforming Laboratory
Mayo Clinic Laboratories in Rochester
Test Classification
This test was developed and its performance characteristics determined by Mayo Clinic in a manner consistent with CLIA requirements. It has not been cleared or approved by the US Food and Drug Administration.CPT Code Information
0361U
LOINC Code Information
| Test ID | Test Order Name | Order LOINC Value |
|---|---|---|
| NFLC | Neurofilament Light Chain, P | 101281-4 |
| Result ID | Test Result Name | Result LOINC Value |
|---|---|---|
| 616854 | Neurofilament Light Chain, P | 101281-4 |
Forms
If not ordering electronically, complete, print, and send a Neurology Specialty Testing Client Test Request (T732) with the specimen.